Alexander Seropian (born 1969) is an American video game developer, one of the initial founders and later president of Bungie, the developer of the Marathon, Myth, and Halo video game series. Seropian became interested in computer programming in college and teamed up with fellow student Jason Jones to publish Jones's game Minotaur: The Labyrinths of Crete. The two became partners, and Bungie grew to become the best-known Apple Macintosh game developer before being bought by Microsoft in 2001.

Michel Mossessian (born 11 November 1959) is a French architect of Armenian origin, based in London, UK.

Tigran Gevorki Chukhajian (1837 – March 11, 1898) was an Ottoman Armenian composer and conductor, and the founder of the first opera institution in the Ottoman Empire. He is considered the first opera composer in Turkish history.

Karen Asrian (24 April 1980 – 9 June 2008) was an Armenian chess player. Awarded the title of Grandmaster by FIDE in 1998, he was a three-time Armenian champion. Asrian was a member of the gold medal-winning Armenian team in the 37th Chess Olympiad.

George Pehlivanian (born 20 April 1964) is a French-American conductor.

Jack Kevorkian (May 26, 1928 – June 3, 2011) was an American pathologist and euthanasia proponent.

Edmen Shahbazyan (born November 20, 1997) is an American mixed martial artist of Armenian descent, competing in the middleweight division of the Ultimate Fighting Championship (UFC). As of November 18, 2019, he is #9 in the UFC middleweight rankings.

Gevorg "Giorgio" Petrosyan (born December 10, 1985) is an Armenian-Italian kickboxer who competes in the middleweight division. Nicknamed "The Doctor" and noted for his supreme technical skills, ringsmanship and defensive prowess which has seen him defeat some of the best strikers in the world while taking little-to-no damage, As of 5 March 2020, he is ranked the #3 lightweight in the world by Combat Press, and is widely regarded as one of the greatest kickboxers of all time.